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The gene at the B locus is called tyrosinase related protein 1 (TYRP1). This gene affects the colour with the eumelanin pigment made, https://waystofreesiteadvert4.edublogs.org/2021/10/04/getting-my-loci-cycle-review-to-work/ which makes it either black or brown. TYRP1 can be an enzyme involved in the synthesis of eumelanin.
DNA scientific tests have isolated a missense mutation from the 20S proteasome βtwo subunit for the H locus.[29] The H locus is usually a modifier locus (from the M locus) and also the alleles within the H locus will figure out if an animal expresses a harlequin vs merle pattern. There's two alleles that manifest with the H locus:
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The alleles for the E locus (the melanocortin receptor a single gene or MC1R) identify whether an animal expresses a melanistic mask, and also deciding whether or not an animal can make eumelanin in its coat. You'll find a few recognized, as well as two much more theorized, alleles that come about for the E locus:
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eh is theorized for being on the E locus and to acquire no effect on ky/ky canine. All cocker spaniels are homozygous for at, so it is unknown how the gene might perform within the existence of other A-sequence alleles.
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